• John Bougearel


Updated: Feb 9


What in the world would I be posting on Acne for? Well, for one, Acne is an indicator of cellular health..

Typically, acne afflicts teenagers undergoing lots of hormonal changes. And hormonal changes always require a good deal of metabolic activity. And this means a great deal of oxidative stress and metabolic waste is created that isn’t getting out of the cell. When we see acne, it reminds us our cells are stressed and dirty.

And indeed, “Emerging studies have shown that patients with acne are under increased cutaneous and systemic oxidative stress. Indeed, there are indications that lipid peroxidation itself is a match that lights an inflammatory cascade in acne. The notion that lipid peroxidation is a 'starter gun' in acne is not a new one.”

Dr Abram Hoffer sees acne as the result of a serious nutritional deficiencies. The cells do not have the nutrients they need to do their job.

Dietary Considerations:

This is where you start, by eliminating the usual offenders, sugars, refined carbs, processed foods, and food allergens. Clean up the diet and supplement with B3, C, B6, and Zinc and most mild to severe acne cases will respond well, says Hoffer.

Further Nutritional Supports:

The antioxidant Glutathione Peroxidase (GSH-Px) can help rid metabolic waste and preventing acne inflammation, says Pizzorno and Murray. GSH It is one of the most critical sulfur containing oxidants, says Michael McEvoy.

The primary role of the GSH=Px enzyme system is to protect cells from oxidative stress. Vit E, B2, and Se can help increase levels of glutathione peroxidase GSH-Px. Vitamin E is one of the most important antioxidants in the skin. It protects sebum from inflammatory damage.

Glutathione or GSH, btw, is comprised of Glycine, Cysteine, and Glutamine. Glycine tends to be the one amino acid that gets hijacked by glysophate, disrupting glycine dependent enzyme systems like GPx. So, removal of glysophate from diet is important, possibly even some glycine supplementation.

NAC is a precursor to GSH. Other co-factors for GSH and GPx are ALA, B6, Se, Vit C, and B2.

GGT (gamma glutamyl transpeptidase) is another enzyme that helps transport the amino acids glycine, cysteine, and glutamine across the cell membrane. If we want adequate GSH-Px levels inside the cell, we better have adequate GGT. Low values of GGT may be due to Mg deficiencies, GSH deficiencies, Amino acid deficiencies, or B6 deficiencies.

Zinc and nicotinamide are both nutrients which support antioxidant pathways, and preliminary clinical trials show value in topical application.

Homeopathic Remedies

Because every person is different, no single homeopathic remedy will work for everyone. A remedy is selected based on a person’s unique set of symptoms, including (but not limited to) their acne symptoms.

1. Hepar Sulph for pimples that are very painful.

2. Calc Sulph for severe cystic acne, especially if prone to ENT Infections

3. Kali Bromatum – acne that continues into adulthood.

4. Pulsatilla – girls at onset of puberty,

5. Silica – for deep hard acne-like boils, esp if prone to ENT infections

6. Sulphur – for oily skin with blackheads and whiteheads.


1. Pizzorno and Murray, Encyclopedia for Natural Medicine

2. https://www.homeopathycenter.org/acne

3. https://www.acneeinstein.com/inflammation-antioxidants-acne/

4. https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-9-141

5. Hoffer, Abram, Niacin


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